Execute the same engine and the same configuration used to validate the bioRxiv preprint, against the locked B01–B10 freeze scope (commit c8b09678). B01–B09 form the 9-target primary blind panel; B10 ADRB2 is retained as the stress-test calibration target and is excluded from the primary macro average, per the preprint. Submissions queue against operator-side GPU infrastructure; logs and results stream back live. Tier 1 returns canonical output; Tier 2 and Tier 3 unlock progressively deeper observability into the gating stack, intermediate manifolds, and device-side traces.